Medicine Supply Notification: Insulin isophane biphasic human 25/75 (Insuman® Comb 25) 100units/ml suspension for injection 3ml cartridge and pre-filled Solostar pens

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Insulin isophane biphasic human 25/75 (Insuman® Comb 25) 100units/ml suspension for injection 3ml cartridge and pre-filled Solostar pens.

MSN/2023/057

Tier 2 – medium impact

Date of issue 6th June 2023

  • Insuman® Comb 25 100units/ml suspension for injection 3ml cartridges and prefilled pens will be discontinued with stocks being exhausted in February and June 2023 respectively.
  • Humulin® M3 remains available, as do other biphasic insulin preparations, and the manufacturers can support a full uplift in supply.

A copy of this medicine supply notification, including further information for pharmacy teams, has been sent to all pharmacy NHS email addresses.

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.