Medicine Supply Notification: Disopyramide (Rythmodan® ) 100mg capsules and disopyramide (Rythmodan Retard® ) 250mg modified-release tablets
Department of Health and Social Care (DHSC) has issued a medicine supply notification for Disopyramide (Rythmodan®) 100mg capsules and disopyramide (Rythmodan Retard®) 250mg modified-release tablets.
MSN/2026/028
Tier 2 – medium impact
Date of issue: 22 June 2026
- Disopyramide (Rythmodan®) 100mg capsules will be in out of stock from late June 2026 until early April 2027.
- Disopyramide (Rythmodan Retard®) 250mg modified release (MR) tablets will be out of stock from late June until late July 2026 and can support a partial uplift in demand once available.
- Parallel imports of disopyramide 250mg MR tablets and disopyramide 100mg capsules are in limited supply and cannot support an uplift in demand.
- Unlicensed imports of disopyramide 100mg capsules and disopyramide 250mg MR tablets have been sourced, lead times vary (see supporting information).
- Unlicensed specials of disopyramide 25mg/5ml and 50mg/5ml oral suspension are available, lead times vary (see supporting information).
Unlicensed products
The following specialist importers have confirmed they can source unlicensed disopyramide 100mg capsules and 250mg MR tablets. Please note there may be other companies that can also source supplies:
- Chemys (100mg capsules)
- Clinigen (both 100mg capsules and 250mg MR tablets)
- Mawdsleys (both 100mg capsules and 250mg MR tablets)
- Target Healthcare (both 100mg capsules and 250mg MR tablets)
The following specials manufacturers have confirmed they can source unlicensed disopyramide liquid (25mg/5ml and or 50mg/5ml oral suspension). Please note there may be other companies that can also source supplies:
If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems, an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘Disopyramide (specify dose and formulation) (Special Order)’ and endorsed by the pharmacy as a non-Part VIII special with the following information:
- Amount dispensed over pack size used;
- Invoice price per pack size from which the order was supplied less any discount or rebate;
- Manufacturers’/importers’ MHRA licence number;
- Batch number of the product supplied;
- SP
A copy of this medicine supply notification, including supporting information, has been sent to all pharmacy NHS email addresses.
DHSC and NHS England have launched an online Medicines Supply Tool, which provides up-to-date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.
The Tool also details any changes to resupply dates and updates to the entries.
To access the Tool you will need an NHS email address. Once set up and logged in, you will be able to access it online.
New shortages not listed on the SPS website, can be reported using our shortage reporting tool.
