Medicine Supply Notification: Edoxaban (Lixiana®) 15mg tablets
The Department of Health and Social Care (DHSC) has issued a medicine supply notification for the following products:
- Edoxaban (Lixiana®) 15mg tablets
MSN/2026/042
Tier 2 – medium impact
Date of issue: 01/09/2026
Summary
- Edoxaban (Lixiana®) 15mg tablets are out of stock until mid-September 2026.
- Alternative direct-acting oral anticoagulants (DOACs) remain available and can support increased demand.
- Unlicensed supplies of Edoxaban 15mg tablets may be sourced, lead times vary.
Unlicensed products
The following specialist importers have confirmed they can source unlicensed Edoxaban 15mg tablets (please note there may be other companies that can also source supplies):
If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘Edoxaban 15mg tablets (Special Order)’ and endorsed by the pharmacy as a non-Part VIII special with the following information:
- Amount dispensed over pack size used;
- Invoice price per pack size from which the order was supplied less any discount or rebate;
- Manufacturers’/importers’ MHRA licence number;
- Batch number of the product supplied;
- SP
Further guidance on how prescriptions for unlicensed specials should be written can be found here.
A copy of this medicine supply notification, including actions required and supporting information, has been sent to all pharmacy NHS email addresses.
DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.
The Tool also details any changes to resupply dates and updates to the entries.
To access the Tool, you will need an NHS email address. Once set up and logged in, you will be able to access it online.
New shortages not listed on the SPS website can be reported using our shortage reporting tool.
