Medicine Supply Notification: Desmopressin 10microgram/dose nasal spray

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Desmopressin 10microgram/dose nasal spray

MSN/2025/010

Tier 2 medium impact

Date of issue: 3rd March 2025

  • Desmopressin 10microgram/dose nasal spray is out of stock with an anticipated re-supply date of early September 2025.
  • Unlicensed supplies of desmopressin 10microgram/dose nasal spray are available, lead times may vary.
  • Desmopressin 100 and 200microgram tablets, desmopressin sublingual tablets and DDAVP Melt oral lyophilisates (60, 120 and 240microgram) remain available and can support an increase in demand (see Supporting information).
  • Desmopressin 4microgram/ml injection is available and can support an increase in demand (see Supporting information).

Unlicensed products

The following specialist importers have confirmed they can source unlicensed desmopressin 10microgram/dose nasal spray (please note there may be other companies that can also source supplies):

If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘Desmopressin 10microgram/dose nasal spray (Special Order)’ and endorsed by the pharmacy as a non-Part VIII special with the following information:

  • Amount dispensed over pack size used;
  • Invoice price per pack size from which the order was supplied less any discount or rebate;
  • Manufacturers’/importers’ MHRA licence number;
  • Batch number of the product supplied;
  • SP

A copy of this medicine supply notification, including further information, has been sent to all pharmacy NHS email addresses.

DHSC and NHS England have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.