Medicine Supply Notification: Capimune® (ciclosporin) 25mg, 50mg and 100mg capsules

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Capimune® (ciclosporin) 25mg, 50mg and 100mg capsules.


Tier 3 – High impact

Date of issue 7th November 2022

  • Capimune® brand of ciclosporin 25mg, 50mg and 100mg capsules are out of stock until mid-December 2022.
  • Deximune® brand of ciclosporin 25mg, 50mg and 100mg capsules remain available and can support a full uplift in demand.
  • Alternative brands of ciclosporin capsules (Neoral®, Vanquoral®, Capsorin®, Sandimmun®) remain available however, have limited or no ability to provide an uplift in demand.

Brand Prescribing

Patients should be stabilised on a particular brand of oral ciclosporin because switching between formulations without close monitoring may lead to clinically important changes in ciclosporin level. Switching between a branded and a generic formulation, or between generic formulations, should be carried out in consultation with the specialist team. If switching is necessary, the patient should be monitored closely for changes in ciclosporin level where clinically appropriate (specialist decision), serum creatinine, blood pressure, disease control/ transplant function, and adverse effects.

A copy of this medicine supply notification, including further information for pharmacy teams, has been sent to all pharmacy NHS email addresses.

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.

Support the call for more funding by recording information about the informal advice you provide to patients over just one day.

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