Medicine Supply Notification: Estradiol (Estradot® ) 50micrograms/24 hours, 75micrograms/24 hours, and 100micrograms/24 hours transdermal patches

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Estradiol (Estradot®) 50micrograms/24 hours, 75micrograms/24 hours, and 100micrograms/24 hours transdermal patches.

MSN/2024/115

Tier 2 – medium impact

Date of issue: 19th December 2024

  • Estradiol (Estradot®) 75micrograms/24hours and 100micrograms/24hours transdermal patches will be out of stock until mid-January 2025
  • Estradiol (Estradot®) 50micrograms/24hours transdermal patches will be out of stock until late February 2025.
  • Alternative brands of estradiol patches (Evorel® and Estraderm MX®) across these strengths are available and can support a full uplift in demand.
  • FemSeven® (estradiol) transdermal patches (once weekly application) remain available and can support an uplift in demand
  • Progynova® (estradiol) transdermal patches also remain available but cannot support an uplift in demand.
  • Serious Shortage Protocols (SSPs) for estradiol (Estradot®) 50micrograms/24 hours, 75micrograms/24 hours and 100micrograms/24 hours transdermal patches were issued on 19/12/2024.

A copy of this medicine supply notification, including further information, has been sent to all pharmacy NHS email addresses.

DHSC and NHS England have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.

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