Medicine Supply Notification: Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution for injection ampoules – Updated
Update 08/05/2024:
Updated information highlighted bold below
Department of Health and Social Care (DHSC) has issued a medicine supply notification for Pabrinex® (Vitamins B and C) Intravenous and Intramuscular High Potency solution
for injection ampoules.
MSN/2024/038
Tier 3 – high impact
Date of issue: 3rd April 2024
- Pabrinex® Intravenous (IV) injection will be out of stock from August 2024 with a resupply date to be confirmed.
- Pabrinex® Intramuscular (IM) injection is being discontinued, with stock exhaustion expected from December 2024.
- Trusts should not seek to replace Pabrinex® IV with supplies of Pabrinex® IM as it cannot support an uplift in demand.
- Supplies of Pabrinex® IM should be reserved for settings where a Patient Group Direction (PGD) is required to supply or administer Pabrinex® IM, where possible.
- There are no other licensed parenteral alternatives to Pabrinex® IV and IM injections.
- Thiamine 50mg and 100mg tablets remain available and should be used where clinically appropriate.
- Unlicensed imports of thiamine injections have been sourced.
Unlicensed products
The following specialist importers have confirmed they can source unlicensed thiamine 50mg/ml or 100mg/ml solution for injection for intramuscular and/ or intravenous use (please note there may be other companies that can also source supplies):
If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘ Thiamine 50mg/ml or 100mg/ml solution for injection (Imported)’ and endorsed by the pharmacy as a non-Part VIIIB special with the following information:
- Amount dispensed over pack size used;
- Invoice price per pack size from which the order was supplied less any discount or rebate;
- Manufacturers’/importers’ MHRA licence number;
- Batch number of the product supplied;
- SP
A copy of this medicine supply notification, including further information, has been sent to all pharmacy NHS email addresses.
DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.
The Tool also details any changes to resupply dates and updates to the entries.
To access the Tool you will need an NHS email address. Once set up and logged in, you will be able to access it online.
New shortages not listed on the SPS website, can be reported using our shortage reporting tool.
