Medicine Supply Notification: Imiquimod (Aldara® ) 5% cream and podophyllotoxin (Warticon® ) 0.5% solution and 0.15% cream

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Imiquimod (Aldara®) 5% cream and podophyllotoxin (Warticon®) 0.5% solution and 0.15% cream

MSN/2024/069

Tier 2 – medium impact

Date of issue: 5th June 2024

  • Imiquimod (Aldara®) 5% cream will be out of stock from mid-June 2024 until late July 2024.
  • Podophyllotoxin (Warticon®) 0.5% solution is out of stock until mid-June 2024.
  • Podophyllotoxin (Warticon®) 0.15% cream is out of stock until mid-October 2024.
  • Imiquimod (Zyclara®) 3.75% cream remains available and can support a partial increase in demand.
  • Imiquimod (Bascellex®) 50 mg/g cream remains available and can support a partial increase in demand.
  • Fluorouracil (Efudix®) 5% cream remains available, however, cannot support any increase in demand.
  • Diclofenac (Solaraze®) 3% gel, fluorouracil with salicylic acid (Actikerall®) cutaneous solution and tirbanibulin (Klisyri®) ointment remain available and can support an increase in demand.
  • Camellia sinensis (Catephen®) 10% ointment remains available and can support a partial increase in demand.
  • Unlicensed supplies of imiquimod 5% cream may be sourced, lead times vary.

Unlicensed products

The following specialist importers have confirmed they can source unlicensed Imiquimod 5% cream (please note there may be other companies that can also source supplies):

If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘ Imiquimod 5% cream (Special Order)’ and endorsed by the pharmacy as a non-Part VIIIB special with the following information:

  • Amount dispensed over pack size used;
  • Invoice price per pack size from which the order was supplied less any discount or rebate;
  • Manufacturers’/importers’ MHRA licence number;
  • Batch number of the product supplied;
  • SP

A copy of this medicine supply notification, including further information, has been sent to all pharmacy NHS email addresses.

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.

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