Medicine Supply Notification: Nortriptyline 10mg/5ml and 25mg/5ml oral solution sugar-free

Department of Health and Social Care (DHSC) has issued a medicine supply notification for Nortriptyline 10mg/5ml and 25mg/5ml oral solution sugar-free


Tier 2 – medium impact

Date of issue: 23rd May 2024

  • Nortriptyline 10mg/5ml oral solution sugar-free has been discontinued; all supplies have now been exhausted
  • Nortriptyline 25mg/5ml oral solution sugar-free will be discontinued from 1st November 2024.
  • Nortriptyline 10mg and 25mg tablets remain available and can support increased demand.
  • Amitriptyline 10mg/5ml and 25mg/5ml oral solution sugar-free remain available and can support increased demand.
  • Unlicensed specials of nortriptyline 10mg/5ml and 25mg/5ml oral suspension sugar-free are available, lead times vary

Unlicensed products

The following Specials manufacturers have confirmed they can manufacture nortriptyline 10mg/5ml and/or 25mg/5ml oral suspension sugar-free (please note there may be other companies that can also manufacture supplies):

If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for the unlicensed product cannot be issued. Where a prescriber wishes to prescribe a specially manufactured or imported product, an FP10 paper prescription should be issued as ‘ nortriptyline 10mg/5ml or 25mg/5ml oral suspension sugar-free (Special Order)’ and endorsed by the pharmacy as a non-Part VIIIB special with the following information:

  • Amount dispensed over pack size used;
  • Invoice price per pack size from which the order was supplied less any discount or rebate;
  • Manufacturers’/importers’ MHRA licence number;
  • Batch number of the product supplied;
  • SP

A copy of this medicine supply notification, including further information, has been sent to all pharmacy NHS email addresses.

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.

Support the call for more funding by recording information about the informal advice you provide to patients over just one day.

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