Medicine Supply Notification: Vial presentations of Hypurin® Porcine Isophane, Hypurin® Porcine Neutral and Hypurin® Porcine 30/70 Mix are being discontinued
The Department of Health and Social Care (DHSC) has issued a medicine supply notification for the following products:
- Hypurin® Porcine Isophane (insulin isophane porcine) 100units/ml suspension for injection 10ml vials
- Hypurin® Porcine Neutral (insulin soluble porcine) 100units/ml solution for injection 10ml vials
- Hypurin® Porcine 30/70 Mix (insulin isophane biphasic porcine 30/70) 100units/ml suspension for injection 10ml vials
MSN/2025/046
Tier 2 – medium impact
Date of issue: 23/07/2025
- Vial presentations of Hypurin® Porcine Isophane, Hypurin® Porcine Neutral and Hypurin® Porcine 30/70 Mix are being discontinued with supplies anticipated to be exhausted by the end of September 2025, mid-February 2026, and end of July 2026, respectively.
- The cartridge presentations of these products remain available and can support increased demand.
- Hypurin® Porcine cartridges are compatible with the AutoPen® Classic, and with the new mypen®2, which will be available from late September 2025.
- Note: AutoPen® Classic has been discontinued but limited stock remains available and can be used until mypen®2 is available (see Supporting information).
A copy of this medicine supply notification, including actions required and supporting information, has been sent to all pharmacy NHS email addresses.
DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.
The Tool also details any changes to resupply dates and updates to the entries.
To access the Tool, you will need an NHS email address. Once set up and logged in, you will be able to access it online.
New shortages not listed on the SPS website can be reported using our shortage reporting tool.
