Medicines that cannot be parallel exported from the UK or hoarded

The following 6 products have been added to the list

• Azithromycin
• Carbamazepine 100mg/5ml oral suspension
• Clarithromycin
• Co-trimoxazole
• Erythromycin
• Pancreatin

The following products have been added, removed and amended to the list:

Added

• Tirzepatide

Removed

• Alfentanil
• Amoxicillin
• Argipressin
• Azithromycin
• Ceftriaxone,
• Clarithromycin
• Clonidine
• Co-amoxiclav
• Codeine
• Conjugated oestrogens and medroxyprogesterone acetate
• Dalteparin
• Diamorphine
• Erythromycin
• Estradiol + Levonorgestrel
• Estriol
• Flucloxacillin
• Gentamicin
• Haloperidol
• Insulin degludec + Liraglutide
• Ketamine
• Levofloxacin
• Lorazepam
• Metaraminol
• Nadolol
• Noradrenaline
• Pantoprazole
• Phenoxymethylpenicillin
• Potassium chloride / Potassium bicarbonate
• Progesterone
• Propofol
• Remifentanil
• Rocuronium
• Tinzaparin
• Voriconazole

Amended

• Exenatide (pharmaceutical form)

The following 2 products have been added to the list:

• Vinblastine 10mg/10ml solution for injection vials
• Aztreonam powder for solution for injection vials

The following product has been added to the list:

• Vitamin B substances with ascorbic acid.

The following product has been added to the list:

• Salbutamol nebuliser liquid unit dose vials

The following 5 products have been added to the list:

• Iodixanol solution for injection
• Iohexol solution for injection
• Nadolol 80mg tablets
• Potassium chloride / Potassium bicarbonate effervescent tablets
• Sodium dihydrogen phosphate anhydrous effervescent tablets

The following product has been added to the list:

• Olanzapine embonate powder and solvent for suspension for injection

The following 7 products have been added to the list:

• Atomoxetine all forms
• Bumetanide all tablets
• Dexamfetamine sulfate all forms
• Guanfacine all forms
• Hyoscine hydrobromide 1.5mg patches
• Lisdexamfetamine mesylate all forms
• Methylphenidate hydrochloride all forms

The following 5 products have been added to the list:

• Bupivacaine + Fentanyl 312.5mg/250ml (0.125%) + 500micrograms/250ml, 625mg/500ml (0.125%) + 1mg/500ml solution for infusion
• Diamorphine, all solution for injection
• Human corticotrophin releasing hormone (hCRH) (Unlicenced) all
• Ketamine all solution for injection
• Levobupivacaine all infusion

The following product has been added to the list:

• Permethrin 5% Cream

The following 5 products have been added to the list:

• Semaglutide, all strengths, tablets;
• Dulaglutide, all strengths, solution for injection;
• Exenatide, all strengths, solution for injection;
• Liraglutide, 6mg/ml, solution for injection;
• Insulin degludec + Liraglutide, 100units/ml + 3.6mg/ml, solution for injection.

The following product has been added to the list:

• Progesterone, 100mg oral capsules

The following 2 products have been added to the list:

• Glucagon: all strengths; powder for injection, solution for injection.

The following 2 products have been added to the list:

• Nirmatrelvir and ritonavir
• Molnupiravir

Three medicines have been added to the list:

• Flucloxacillin
• Oseltamivir
• Zanamivir.

Further presentations of 2 medicines have been added to the list:

• Amoxicillin oral suspension and oral solution
• Phenoxymethylpenicillin (Penicillin V) oral suspension and oral solution.

Ten medicines have been removed from the list of medicines intended for the UK market that cannot be exported from the UK. They are:

• Anakinra
• Budesonide
• Calcium chloride
• Colestyramine
• Dexmedetomidine
• Epoprostenol
• Milrinone
• Rifampicin
• Rivaroxaban
• Salbutamol

Insulin human has been removed as this is the same product as insulin soluble human.

A further 4 products have been added to the list. These are:

• Amoxicillin
• Cefalexin
• Phenoxymethylpenicillin (Penicillin V)
• Azithromycin oral suspension.

Added semaglutide to the list.

Two medicines have been added to the list:

• Alteplase
• Tenecteplase.

32 medicines have been removed from the list of medicines intended for the UK market that cannot be exported from the UK. They are:

• Albumin human
• Adrenaline
• Amikacin
• Amoxicillin
• Anidulafungin
• Bupropion
• Caspofungin
• Cefalexin
• Ceftazidime + Avibactam
• Dabigatran etexilate
• Dapagliflozin
• Dobutamine
• Esmolol
• Flucloxacillin
• Glyceryl trinitrate
• Granisetron
• Ketamine
• Lansoprazole
• Magnesium Sulfate
• Metoclopramide
• Micafungin
• Morphine
• Ondansetron
• Potassium bicarbonate + Potassium chloride
• Potassium chloride + Glucose + Sodium chloride
• Potassium chloride + Sodium chloride
• Ranitidine
• Ruxolitinib
• Sodium chloride
• Sodium dihydrogen phosphate
• Sodium lactate and Terlipressin.

Two medicines have been added to the list:

• Conjugated oestrogens
• medroxyprogesterone acetate and Estriol.

Updated the list to include one missing product:

• Amiodarone – solution for injection.

Updated list of medicines to reflect that 47 medicines have been removed from the list:

• Aclidinium bromide
• Aclidinium bromide + Formoterol
• Amiodarone
• Bambuterol
• Beclometasone + Formoterol
• Beclometasone + Formoterol + Glycopyrronium bromide
• Benralizumab
• Ciclesonide
• Edoxaban
• Exenatide
• Fluticasone + Formoterol
• Fluticasone + Salmeterol
• Fluticasone + Umeclidinium bromide + Vilanterol
• Fluticasone + Vilanterol
• Formoterol
• Insulin aspart
• Insulin aspart biphasic
• Insulin degludec
• Insulin degludec + Liraglutide
• Insulin detemir
• Insulin glargine
• Insulin glargine + Lixisenatide
• Insulin glulisine
• Insulin isophane biphasic human
• Insulin isophane biphasic porcine
• Insulin isophane bovine
• Insulin isophane human
• Insulin isophane porcine
• Insulin lispro
• Insulin lispro biphasic
• Insulin mixed bovine
• Insulin protamine zinc bovine
• Insulin soluble bovine
• Insulin soluble porcine
• Insulin zinc crystalline human
• Insulin zinc mixed human
• Lithium carbonate
• Lopinavir + Ritonavir
• Mesalazine
• Norethisterone
• Oseltamivir
• Pneumococcal vaccine
• Roflumilast
• Semaglutide
• Ticagrelor
• Tiotropium
• Tiotropium + Olodaterol.

Bupropion tablets added to the restricted export list.

Updated list of medicines to supplement the previous update of 30 October 2020. The new, shorter list comes into effect on 3 August 2021. 30 medicines have been removed from the list of medicines intended for the UK market that cannot be exported from the UK. They are:

• Atenolol
• Beclometasone
• Bisoprolol
• Budesonide + Formoterol
• Buprenorphine
• Buprenorphine
• Chloroquine phosphate
• Digoxin
• Estradiol + Norethisterone acetate
• Fluticasone
• Ondansetron
• Plasma-Lyte
• Salbutamol + Beclometasone
• Sodium chloride
• Granisetron
• Ibuprofen
• Ipratropium
• Labetalol
• Lisinopril
• Sodium zirconium cyclosilicate
• Metoprolol
• Mometasone
• Nedocromil
• Terbutaline
• Terbutaline
• Prednisolone
• Salbutamol + Ipratropium
• Salmeterol
• Sodium cromoglicate
• Sodium cromoglicate + Salbutamol.

Updated details section to state that from 1 January 2021 you may no longer be able to export branded medicines that have been placed on the UK market to countries in the European Economic Area (EEA). You should check the guidance on changes to the exhaustion of Intellectual Property rights and parallel trade from 1 January 2021.

Two medicines have been added to the list:

• dabigatran etexilate
• semaglutide.

The date of restriction is 00:00am at the start of 7 November 2020.

Updated list of medicines to replace previous update from 30 October. The restriction start date is 31/10/2020 00:00.
27 medicines have been removed from the list of medicines that cannot be parallel exported from the UK. They are:

• Alprostadil
• Azathioprine
• Colecalciferol + Calcium carbonate
• Conjugated oestrogens
• Conjugated oestrogens + Bazedoxifene
• Conjugated oestrogens + Medroxyprogesterone
• Dabigatran
• Doxycycline
• Enoxaparin
• Estradiol + Dydrogesterone
• Estradiol + Medroxyprogesterone
• Estradiol + Norgestrel
• Estriol
• Furosemide
• Hepatitis A + B vaccine
• Hydroxychloroquine
• Levonorgestrel
• Measles + Mumps + Rubella vaccine
• Medroxyprogesterone
• Meropenem
• Misoprostol
• Omeprazole
• Ospemifene
• Prazosin
• Progesterone
• Teicoplanin
• Tibolone.

2 medicines have been added to the list:

• Influenza vaccine
• Anakinra.

The pharmaceutical forms for Co-trimoxazole and Hydrocortisone have been updated.

27 medicines have been removed from the list of medicines that cannot be parallel exported from the UK. They are:

• Alprostadil
• Azathioprine
• Colecalciferol + Calcium carbonate
• Conjugated oestrogens
• Conjugated oestrogens + Bazedoxifene
• Conjugated oestrogens + Medroxyprogesterone
• Dabigatran
• Doxycycline
• Enoxaparin
• Estradiol + Dydrogesterone
• Estradiol + Medroxyprogesterone
• Estradiol + Norgestrel
• Estriol
• Furosemide
• Hepatitis A + B vaccine
• Hydroxychloroquine
• Levonorgestrel
• Measles + Mumps + Rubella vaccine
• Medroxyprogesterone
• Meropenem
• Misoprostol
• Omeprazole
• Ospemifene
• Prazosin
• Progesterone
• Teicoplanin
• Tibolone.

2 medicines have been added to the list:

• Influenza vaccine
• Anakinra.

The pharmaceutical forms for Co-trimoxazole and Hydrocortisone have been updated.

Lithium carbonate has been added to the list of medicines.

Two pharmaceutical forms of dexamethasone (oral solution and solution for injection) have been added to the list of medicines. The date of restriction is 00:00am at the start of 16 June 2020.

33 medicines have been added to the parallel export list and the pharmaceutical forms of 5 medicines have also been updated.

• Aclidinium bromide
• Aclidinium bromide + Formoterol
• Atenolol
• Azithromycin
• Bambuterol
• Benralizumab
• Bisoprolol
• Buprenorphine
• Ceftazidime + Avibactam
• Cyclizine
• Dabigatran etexilate
• Dapagliflozin
• Dexamethasone
• Digoxin
• Exenatide
• Glycopyrronium bromide
• Haloperidol
• Hyoscine butylbromide
• Ibuprofen
• Labetalol
• Lisinopril
• Metaramino
• Metoprolol
• Pantoprazole
• Roflumilast
• Ruxolitinib
• Sarilumab
• Sodium zirconium cyclosilicate
• Ticagrelor
• Tiotropium
• Tiotropium + Olodaterol and Tocilizumab.

The date of restriction for updates made on 3 April 2020 has been amended.

Discrepancies between ‘strength’ and ‘pharmaceutical form’ have been corrected in the list of medicines that cannot be parallel exported from the UK.

52 medicines have been added to the list of medicines that cannot be parallel exported from the UK, these are:

• Cefalexin
• Codeine
• Co-trimoxazole
• Diamorphine
• Doxycycline
• Ipratropium
• Salbutamol
• Prochlorperazine
• Salbutamol + Beclometasone
• Salbutamol + Ipratropium Terbutaline,
• Beclometasone
• Beclometasone + Formoterol
• Beclometasone + Formoterol + Glycopyrronium bromide
• Budesonide
• Budesonide + Formoterol
• Fluticasone
• Fluticasone + Formoterol
• Fluticasone + Salmeterol
• Fluticasone + Umeclidinium bromide + Vilanterol
• Fluticasone + Vilanterol
• Ciclesonide
• Mometasone
• Salmeterol
• Formoterol
• Sodium cromoglicate
• Sodium cromoglicate + Salbutamol
• Nedocromil
• Edoxaban
• Midazolam
• Buprenorphine
• Levomepromazine
• Mesalazine
• Colecalciferol + Calcium carbonate
• Insulin aspart
• Insulin aspart biphasic
• Insulin degludec
• Insulin degludec + Liraglutide
• Insulin detemir
• Insulin glargine
• Insulin glargine + Lixisenatide
• Insulin glulisine
• Insulin human
• Insulin isophane biphasic human
• Insulin isophane biphasic porcine
• Insulin isophane bovine
• Insulin isophane human
• Insulin isophane porcine
• Insulin lispro
• Insulin lispro biphasic
• Insulin mixed bovine
• Insulin protamine zinc bovine
• Insulin soluble bovine
• Insulin soluble human
• Insulin soluble porcine
• Insulin zinc crystalline human
• Insulin zinc mixed human.

The pharmaceutical forms of several medicines have been updated to clarify which pharmaceutical forms are included in the restrictions.

Several names of medicines have been updated to align with the NHS dictionary of medicines and devices. The pharmaceutical forms of several medicines have been updated to clarify which pharmaceutical forms are included in the restrictions. Duplications have been removed.

82 medicines have been added to the list of medicines that cannot be parallel exported from the UK. The medicines added to the list are:

• Accusol 35
• Albumin
• Alfentanil
• Amikacin
• Amiodarone
• Amoxicillin
• Anidulafungin
• Argipressin
• Atracurium
• Calcium
• Caspofungin
• Ceftazidime
• Ceftriaxone
• Cefuroxime
• Cisatracurium
• Clarithromycin
• Clonidine
• Co-amoxiclav
• Cyclizine
• Dalteparin
• Dexmedetomidine
• Dobutamine
• Enoxaparin
• Epoprostenol
• Erythromycin
• Esmolol
• Esomeprazole
• Fentanyl
• Flucloxacillin
• Furosemide
• Plasma-Lyte
• Gentamicin
• Glyceryl trinitrate
• Granisetron
• Heparin sodium
• Hydrocortisone
• Hemolactol
• Hemosol B0
• Insulin
• Ketamine
• Lansoprazole
• Levofloxacin
• Linezolid
• Lorazepam
• Lactasol
• Magnesium
• Meropenem
• Metoclopramide
• Micafungin
• Midazolam
• Milrinone
• Morphine
• Morphine sulfate
• Monosul
• Noradrenaline
• Omeprazole
• Ondansetron
• Ondansetron
• Oxycodone
• Pantoprazole
• Paracetamol
• Piperacillin
• Potassium chloride
• Prednisolone
• Propofol
• Prismasol 4
• PrismOcal B22
• Prismocitrate 18/0
• Potassium chloride
• Ranitidine
• Remifentanil
• Rifampicin
• Rocuronium
• Sodium chloride
• Sodium dihydrogen phosphate
• Sodium lactate
• Suxamethonium
• Teicoplanin
• Terlipressin
• Tinzaparin
• Vancomycin
• Voriconazole.

The date of restriction is 00:00am at the start of 21 March 2020.

One medicine has been added to the list of medicines that cannot be parallel exported from the UK:

• Hydroxychloroquine

The date of restriction is 00:00am at the start of 14 March 2020.

Three medicines have been added to the list of medicines that cannot be parallel exported from the UK:

• Lopinavir + Ritonavir
• Chloroquine phosphate
• Azathioprine.

The date of restriction is 00:00am at the start of 26 February 2020.

Inconsistencies in the naming of medicines have been addressed and names now follow the ‘Dictionary of medicines and devices (dm+d)’. The restrictions are on the virtual therapeutic moiety (VTM) unless the actual medicinal product (AMP) is listed.

One medicine has been removed from the list of medicines that cannot be parallel exported from the UK:

• Alogliptin

Two medicines have been added to the list of medicines that cannot be parallel exported from the UK:

• colestyramine sachets
• fluticasone propionate nasules.

One medicine has been added to the list of medicines that cannot be parallel exported from the UK:

• hepatitis A and B vaccine.

The date of restriction is 00:00am at the start of 14 November 2019.

Four medicines have been added to the list of medicines that cannot be parallel exported from the UK:

• alogliptin/metformin
• pneumococcal polysaccharide vaccine
• measles, mumps and rubella vaccine
• misoprostol.

The date of restriction is 00:00am at the start of 6 November 2019.

Four medicines have been added to the list of medicines that cannot be parallel exported from the UK: alprostadil, beclometasone dipropionate, noresthisterone and ranitidine. The date of restriction is 00:00am at the start of 18 October 2019.

The ‘Date of publication’ column has been removed from the list of medicines that cannot be parallel exported from the UK. This is to avoid confusion with the ‘Date of restriction’ column

A link to guidance on ‘Parallel export and hoarding of restricted medicines’ has been added to the details text.

Added link to letter to holders of a wholesale dealer licence.

First published.